INTEGRATION OF GENOMIC ANALYSIS AND TRANSCRIPT EXPRESSION OF ABCC8 AND KCNJ11 IN FOCAL FORM OF CONGENITAL HYPERINSULINISM

Integration of genomic analysis and transcript expression of ABCC8 and KCNJ11 in focal form of congenital hyperinsulinism

BackgroundThe focal form of CHI is caused by an autosomal recessive pathogenic variant affecting the paternal homologue of genes ABCC8 or KCNJ11 and a Twin Sleigh Storage Bed second somatic event specifically occurring in the affected islet of Langerhans.The approach of this study was to integrate the genetic changes occurring in pancreatic focal l

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The effects of auditory stimulation on heart rate variability in healthy individuals with normal hearing and with hearing loss: a systematic review and meta-analysis

ABSTRACT Purpose To analyze the effects of auditory stimulation on heart rate variability (HRV) indices in healthy individuals with normal hearing and with hearing loss, regardless of type and/or grade, by means of a systematic review.Research strategies This is a systematic review with a meta-analysis that addresses the following question: in heal

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Identification of key peptidoglycan hydrolases for morphogenesis, autolysis, and peptidoglycan composition of Lactobacillus plantarum WCFS1

Abstract Background Lactobacillus plantarum is commonly used in industrial fermentation processes.Selected strains Charger are also marketed as probiotics for their health beneficial effects.Although the functional role of peptidoglycan-degrading enzymes is increasingly documented to be important for a range of bacterial processes and host-microbe

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